TPOT Case Studies

49 yr old IDDM white male with traumatic tissue injury to 5th tarsal; arrived at ER with emergency amputation scheduled; patient sought second opinion before proceeding; systemic infection treated with antibiotics; patient received Topical Pressurized Oxygen Therapy (TPOT) for 90 minutes a day, 5 days a week. Wound debrided weekly. The 5th tarsal was amputated. Complete closure of the wound was achieved within 65 treatments. Patient's wound remains unremarkable.

– Dr. E. Blackman, MD, FRCS(c), St. Catharines, ON

October 23, 2006

November 10, 2006

February 9, 2007

62 yr old white male IDDM; prior 4thand 5thtarsal amputation at the methead. Plantar surface diabetic/neuropathic foot ulcer developed with Osteo present. This patient was scheduled for BKA prior to being seen by Dr. Blackman in clinic. Patient treated with antibiotics, received weekly sharp debridement until wound came to full closure using Topical Pressurized Oxygen Therapy (TPOT)

– Dr. E. Blackman, MD, FRCS(c), St. Catharines, ON

November 17, 2006

February 28, 2007

42 yr old IDDM aboriginal male suffering from a Wagner Grade 3 with Osteomyelitis present for 6 years, non healing with traditional methods; Prior V.A.C.™ use with no result; healed in 28 treatments using Topical Pressurized Oxygen Therapy (TPOT).

– Valerie Winberg, RN(EC), BScN, MN, NP-PHC, ENC(c), IIWCC, Walpole Island, ON

January 12, 2010

February 8, 2010

March 15, 2010

57 yr old non-Caucasian male, IDDM with Diabetic/neuropathic foot ulcer to the dorsal surface of the right foot; Multiple treatment modalities were attempted with no response; Topical Pressurized Oxygen Therapy (TPOT) was started after sharp debridement with full wound closure achieved in 44 treatments. Patient retained limb and remains unremarkable.

– TSS Woundcare

February 7, 2008

February 15, 2008

April 12, 2008

57 y/o w male with Bilateral BKA with IDDM. Left leg BKA 6 years prior due to sepsis to left foot DFU. A DFU developed on the right foot shortly thereafter which became septic and a right foot amputation then ensued. Due to PAD, a right BKA was performed which dehisced and became septic. A sinus then formed 6 cm along the periosteum. Osteomyelitis was ruled out via radiological exam. The patient was placed on topical antimicrobials and systemic antibiotics yet the wound had stalled. Topical Pressurized Oxygen was used as a last attempt to salvage the limb and avoid another surgery. The wound responded forming a nice bed of granulation tissue and complete closure of the sinus within 44 treatments. TPOT continued until November 1st when the surgeons decided to flap the remaining area.

– Dr. Kevin Y. Woo PhD RN ACNP GNC(C) FAPWCA, West Park Healthcare Centre, Toronto, ON

August 6, 2010

October 5, 2010

November 1, 2010

79 yr old white female, with 2 stasis ulcers to the left tibia. Patient received Topical Pressurized Oxygen Therapy (TPOT) 90 minutes a day, 5 days a week. The wound received a moist/dry dressing post therapy, and a compression garment was applied. Closure achieved after 140 days. Compression therapy was continued post wound closure. Patient remains wound free with no signs of reoccurrence. Funded by HINF.

– TSS Woundcare, Huntsville, ON

July 30, 2008

December 17, 2008

47 yr old white male, paraplegic, suffered a left fractured tib fib from skydiving accident. Best Practice models were followed for 6 years with no improvement; Patient sought second opinion from the orthopedic surgeon who recommended Topical Pressurized Oxygen Therapy (TPOT) which was started October 1st. Wound was debrided weekly with full closure achieved within 102 days.

– Dr. Andrew Quinn, MD FRCS(c), William Osler Health System, ON

October 1, 2010

October 18, 2010

January 10, 2011

57 yr old white male, IDDM, renal failure; COPD. Patient developed Wagner Grade 3 DFU. The 4thtarsal at the methead was removed on week 4 of therapy. Patient received Topical Pressurized Oxygen Therapy (TPOT) two hours per day during dialysis. A nice bed of granulation tissue formed; the wound was debrided from callous on a weekly basis. There was a sinus present between the 3rdand 5thtarsal approximately 4cm in depth, was closed after week 3. Patient was supposed to receive BKA, but due to the success with TPOT, patient retained his limb and has received the proper offloading for ambulation.

– Maria Scattolon RN, MSN, NP, St. Joseph's Hospital, Hamilton, ON

September 23, 2010

October 28, 2010

51 yr old white male, IDDM, has received multiple courses of systemic antibiotics inclusive with Best Practice model. The patient received in home nursing care as well as hospital visits resulting in both feet being bandaged. This patient has uses silver products, hydrogels, and monthly application of Regranex to no avail. Topical Pressurized Oxygen Therapy (TPOT)started August 11th, with moist/dry dressings applied post TPOT. Closure achieved after 51 treatments of TPOT.

– Dr. Craig Pearce, MD MB ChB FRCS(C), Windsor, ON

August 11, 2010

August 25, 2010

October 21, 2010

32 yr old white female, suffers from venous stasis. Did not respond well to Best Practice model. Topical Pressurized Oxygen Therapy (TPOT) started September 7, compression bandages were applied post TPOT treatments. As of November 5, the wound is almost closed and is responding well to continuous compression application.

– TSS Woundcare, Windsor, ON

September 7, 2010

November 5, 2010

57 yr old white male, IDDM. This patient has been suffering from multiple surgeries to include TMA 2005 and multiple re-sections over the years. He has been on V.A.C.™ three times to no avail. This patient received 40 dives of traditional hyperbaric medicine with no wound response. The patient was slated to receive a BKA but at the request of his surgeon, Topical Pressurized Oxygen Therapy (TPOT) was initiated as a last ditch effort to save the limb. The wound responded positively to 90% closure within 15 treatments of TPOT. The patient remains on TPOT until closure is achieved.

– Dr. Richard Sheppeck MD, Hamot Medical Centre, Erie, PA, USA

December 15, 2010

December 29, 2010

January 5, 2011

35 yr old white female, victim of a motor vehicle accident, where she was dragged by the undercarriage of the car for several hundred feet. She had underwent many debridements and a graft application. The wound would not respond to Best Practice models due to the hypoxia suffered by the graft. Topical Pressurized Oxygen Therapy (TPOT) was applied via Multi-purpose Bag. As the wound responded positively over the next 12 treatments. Epithelialization is beginning to form after a nice bed of granulation tissue had been achieved. The wound is now being addressed with Best Practice models and continues to progress.

– Rose Raizman RN, MSc, CETN (c) CNS, Enterostomal Therapist, Rouge Valley Hospital, ON

November 30, 2010

December 15, 2010

January 11, 2011

46 yr old white male, IDDM suffered from a traumatic injury to his right great toe. The toe developed an ulcer which immediately became septic. The patient received several courses of antibiotics for sepsis and osteomyelitis. The wound progressed to exposed bone and the patient was slated for amputation of the great toe. The patient refused the diagnosis of amputation and sought a second opinion. The new practitioner chose to utilize Topical Pressurized Oxygen Therapy (TPOT) in an effort to save the great toe. The exposed bone developed coverage of granulation tissue within 6 treatments. TPOT was continued until closure was achieved and the patient retained his great toe. (to date there has been no reoccurrence of the wound since closure).

– Valerie Winberg, RN(EC), BScN, MN, NP-PHC, ENC(c), IIWCC, Chatham, ON

May 3, 2010

June 2, 2010

September 9, 2010